Sunday, December 22, 2013

Cellular Traffic Control System Research Earns the Nobel Prize

Keeps Activities Inside Cells From Descending Into Chaos

Earlier this year the Nobel Prize in medicine was awarded to three scientists for their work on how tiny vesicles shuttle the right chemicals to the right location at the right time within the cell. It is an elaborate traffic control system at the molecular level. Here is how the Associated Press described the work:

This traffic control system ensures that the cargo is delivered to the right place at the right time and keeps activities inside cells from descending into chaos, the committee said. Defects can be harmful, leading to neurological diseases, diabetes and disorders affecting the immune system.

"Imagine hundreds of thousands of people who are traveling around hundreds of miles of streets; how are they going to find the right way? Where will the bus stop and open its doors so that people can get out?" Nobel committee secretary Goran Hansson said. "There are similar problems in the cell."

And here is how the Nobel Prize press release describes the work:

The 2013 Nobel Prize honours three scientists who have solved the mystery of how the cell organizes its transport system. Each cell is a factory that produces and exports molecules. … These molecules are transported around the cell in small packages called vesicles. The three Nobel Laureates have discovered the molecular principles that govern how this cargo is delivered to the right place at the right time in the cell. …

Through their discoveries, Rothman, Schekman and Südhof have revealed the exquisitely precise control system for the transport and delivery of cellular cargo. Disturbances in this system have deleterious effects and contribute to conditions such as neurological diseases, diabetes, and immunological disorders.

In a large and busy port, systems are required to ensure that the correct cargo is shipped to the correct destination at the right time. The cell, with its different compartments called organelles, faces a similar problem: cells produce molecules such as hormones, neurotransmitters, cytokines and enzymes that have to be delivered to other places inside the cell, or exported out of the cell, at exactly the right moment. Timing and location are everything. Miniature bubble-like vesicles, surrounded by membranes, shuttle the cargo between organelles or fuse with the outer membrane of the cell and release their cargo to the outside. This is of major importance, as it triggers nerve activation in the case of transmitter substances, or controls metabolism in the case of hormones. How do these vesicles know where and when to deliver their cargo?

Without this wonderfully precise organization, the cell would lapse into chaos.

The award encompasses research that was done by many teams over several decades. Not surprisingly there is no scientific explanation for how such a traffic control system evolved. All that evolutionists can offer is vague narratives about how evolution constructed primitive versions of the system which later were improved upon. Nonetheless evolutionists argue vigorously that evolution is a fact.

1 comment:

  1. 'Without this wonderfully precise organization, the cell would lapse into chaos.'

    But, but... chaos is very good at designing and producing things.

    Seriously, this had me doubled up with laughter:

    ' Not surprisingly there is no scientific explanation for how such a traffic control system evolved.'

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